Epidemiological and clinical characteristics of prostate cancer in a regional hospital in Peru, 2017-2022
DOI:
https://doi.org/10.51252/rsayb.v4i1.884Keywords:
adenocarcinoma, Gleason scale, mestizo, prostatitisAbstract
Prostate cancer is the most common urological neoplasm and a leading cause of mortality in adult men. Its slow growth and asymptomatic course lead to late diagnosis in advanced stages, significantly reducing the chances of effective treatment. To determine the epidemiological and clinical characteristics of prostate cancer in patients treated at a regional hospital in Peru, 2017-2022. Basic type study, simple descriptive, retrospective and cross-sectional, with a population of 231 and a sample of 52 patients. Use of a data collection form for patients aged 50 to 89 years diagnosed with prostate cancer in the period 2017-2022. The majority of patients were between 70 and 79 years old (50%) and were mestizo (98%), with 60% coming from rural areas. Prostatitis was present in 69% of cases, 100% with a palpable nodule, 71% with PSA >25 ng/ml, Gleason score 5-7 (G2-G3) in 49%, clinical stage T2 in 64%, and adenocarcinoma in 88% of cases. Prostate cancer was more common in men older than 70 years, of mixed race, and from rural areas, with a history of prostatitis and elevated PSA levels. Adenocarcinoma was the predominant histological type, associated with localized clinical stages and moderate Gleason differentiation.
Downloads
References
Reina-Reina, Ismael. Cribado del cáncer de próstata. ¿Realmente hacemos lo que nos recomiendan las guías de práctica clínica? 2021 [cited 2023 Jul 15]; Available from: https://digibug.ugr.es/handle/10481/69183
García-Perdomo HA, Zapata-Copete JA. Una mirada global y actualizada del cáncer de próstata. Revista de la Facultad de Medicina [Internet]. 2018 Jul 1 [cited 2023 Jul 15];66(3):429–37. Available from: http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0120-00112018000300429&lng=en&nrm=iso&tlng=es
El INS - CENSOPAS publica portal web de Agentes Cancerígenos en el ambiente de trabajo [Internet]. [cited 2023 Jul 15]. Available from: https://web.ins.gob.pe/es/prensa/noticia/el-ins-censopas-publica-portal-web-de-agentes-cancerigenos-en-el-ambiente-de-trabajo
Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018 Nov;68(6):394–424. Available from: https://doi.org/10.3322/caac.21492
Schatten H. Brief Overview of Prostate Cancer Statistics, Grading, Diagnosis and Treatment Strategies. Adv Exp Med Biol [Internet]. 2018 [cited 2023 Sep 4];1095:1–14. Available from: https://pubmed.ncbi.nlm.nih.gov/30229546/
Wei J, Barocas D, Carlsson S. Early Detection of Prostate Cancer: AUA/SUO Guideline (2023) - American Urological Association [Internet]. [cited 2023 Jul 15]. Available from: https://www.auanet.org/guidelines-and-quality/guidelines/early-detection-of-prostate-cancer-guidelines
REUNIS: Repositorio Único Nacional de Información en Salud - Ministerio de Salud [Internet]. [cited 2023 Jul 15]. Available from: https://www.minsa.gob.pe/reunis/data/tasas_mortalidad.asp
» INEN: ¿El cáncer de próstata se puede prevenir?Instituto Nacional de Enfermedades Neoplásicas [Internet]. [cited 2023 Jul 15]. Available from: https://portal.inen.sld.pe/inen-el-cancer-de-prostata-se-puede-prevenir-2/
Centro Nacional de Epidemiología, Prevención y Control de Enfermedades Ministerio de Salud del Perú Calle Daniel Olaechea 199-Jesús María Lima-Perú. [cited 2023 Jul 15]; Available from: http://www.dge.gob.pe
Islas Pérez LÁ, Martínez Reséndiz JI, Ruiz Hernández A, Ruvalcaba Ledezma JC, Benítez Medina A, Beltran Rodríguez MG, et al. Epidemiología del cáncer de próstata, sus determinantes y prevención. Journal of Negative and No Positive Results [Internet]. 2020 [cited 2023 Jul 15];5(9):1010–22. Available from: https://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S2529-850X2020000901010&lng=es&nrm=iso&tlng=es
Gutiérrez RR, Álvarez M. Lugar de residencia y grado de marginación como factores pronóstico de supervivencia al cáncer de próstata en Veracruz, México. Rev Peru Med Exp Salud Publica. 2020;37(3). Available from: http://dx.doi.org/10.17843/rpmesp.2020.373.4929
Rubí-López B, José Real-Cárabes J, Magaña-Gutiérrez A, Iván Ibarra-Navarro E, de Jesús Andrade-Pérez F, Sánchez-Mejía P, et al. Cáncer de próstata en México: experiencia epidemiológica en el Nuevo Hospital Civil de Guadalajara “Dr. Juan I. Menchaca.” Rev Mex Urol [Internet]. 2020 Jan 13 [cited 2023 Jul 15];80(6):1–8. Available from: https://revistamexicanadeurologia.org.mx/index.php/rmu/article/view/704
Galindo Pasache JA. Características clínicas y paremiológicas del cáncer de próstata de pacientes tratados en el Hospital Augusto Hernández Mendoza ESSALUD Ica, 2015 al 2019. 2021 [cited 2023 Jul 15]; Available from: https://repositorio.unica.edu.pe/handle/20.500.13028/3431
Reyes S. Obesidad como factor de riesgo a cáncer de próstata en el servicio de urología de la Clínica Detecta, 2016 – 2019, Lima Perú. Universidad Privada San Juan Bautista [Internet]. 2020 [cited 2023 Jul 15]; Available from: http://repositorio.upsjb.edu.pe/handle/20.500.14308/2499
Barranzuela Acosta M. Perfil clínico epidemiológico y terapéutico del cáncer de próstata en un hospital de nivel III de Chiclayo. Repositorio Institucional - UCV [Internet]. 2020 [cited 2023 Jul 15]; Available from: https://repositorio.ucv.edu.pe/handle/20.500.12692/41471
Jauregui E. Características clínica epidemiológica según grupo etario en cáncer de próstata en pacientes de 40 a 99 años que acuden al servicio de urología del Hospital Nacional Hipólito Unánue durante el periodo 2015-2016. Universidad Privada San Juan Bautista [Internet]. 2018 [cited 2023 Jul 15]; Available from: http://repositorio.upsjb.edu.pe/handle/20.500.14308/1579
Vallejos J, Villaronga B A, Álvarez C, Mariluis C, Paganini L, González C, et al. Actualización de la estadificación del cáncer de próstata. Revista argentina de radiología [Internet]. 2018 [cited 2023 Jul 15];77(4):0–0. Available from: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1852-99922013000400009&lng=es&nrm=iso&tlng=es
Robles A, Rocío T. La próstata:generalidades y patologías más frecuentes. Revista de la Facultad de Medicina de la UNAM. 2019 Oct 16;62:41–54. Available from: https://doi.org/10.22201/fm.24484865e.2019.62.4.07
Signos y síntomas del cáncer de próstata | American Cancer Society [Internet]. [cited 2023 Jul 15]. Available from: https://www.cancer.org/es/cancer/tipos/cancer-de-prostata/deteccion-diagnostico-clasificacion-por-etapas/senales-sintomas.html
Recomendaciones de la Sociedad Americana Contra El Cáncer para la detección temprana del cáncer de próstata | American Cancer Society [Internet]. [cited 2023 Jul 15]. Available from: https://www.cancer.org/es/cancer/tipos/cancer-de-prostata/deteccion-diagnostico-clasificacion-por-etapas/recomendaciones-de-la-sociedad-americana-contra-el-cancer.html
Naji L, Randhawa H, Sohani Z, Dennis B, Lautenbach D, Kavanagh O, et al. Digital Rectal Examination for Prostate Cancer Screening in Primary Care: A Systematic Review and Meta-Analysis. Ann Fam Med [Internet]. 2018 Mar 1 [cited 2023 Jul 15];16(2):149–54. Available from: https://pubmed.ncbi.nlm.nih.gov/29531107/
Prueba del antígeno prostático específico (PSA) - NCI [Internet]. [cited 2023 Jul 16]. Available from: https://www.cancer.gov/espanol/tipos/prostata/hoja-informativa-psa
Pruebas para diagnosticar y determinar la etapa del cáncer de próstata | American Cancer Society [Internet]. [cited 2023 Jul 15]. Available from: https://www.cancer.org/es/cancer/tipos/cancer-de-prostata/deteccion-diagnostico-clasificacion-por-etapas/como-se-diagnostica.html
Estadificación del cáncer | American Cancer Society [Internet]. [cited 2023 Jul 16]. Available from: https://www.cancer.org/es/cancer/diagnostico-y-etapa-del-cancer/estadificacion-del-cancer.html
Bolaños P, Chacón C. Escala patológica de Gleason para el cáncer de prostata y sus modificaciones [Internet]. [cited 2023 Jul 16]. Available from: https://www.scielo.sa.cr/scielo.php?script=sci_arttext&pid=S1409-00152017000100237
Cancer Staging Manual [Internet]. 8th ed. Vol. 8. 2017 [cited 2023 Dec 1]. Available from: https://www.cancer.net/es/tipos-de-cancer/cancer-de-prostata/estadios-y-grados
Aguilar A. Comité de guías de práctica clínica ONCOSALUD-AUNA. [cited 2023 Jul 15]; Available from: http://portal.guiasalud.es/web/guest/hom
Lynch HT, Kosoko-Lasaki O, Leslie SW, Rendell M, Shaw T, Snyder C, et al. Screening for familial and hereditary prostate cancer. Int J Cancer [Internet]. 2016 Jun 1 [cited 2023 Jul 15];138(11):2579–91. Available from: https://pubmed.ncbi.nlm.nih.gov/26638190/
Larsson Id SC, Carter P, Id SK, Id MV, Mason Id AM, Michaë Lsson K, et al. Smoking, alcohol consumption, and cancer: A mendelian randomisation study in UK Biobank and international genetic consortia participants. 2020 [cited 2023 Sep 10]; Available from: https://doi.org/10.1371/journal.pmed.1003178
Wilson RL, Taaffe DR, Newton RU, Hart NH, Lyons-Wall P, Galvão DA. Obesity and prostate cancer: A narrative review. Critical Reviews in Oncology / Hematology [Internet]. 2022 [cited 2023 Sep 10];169:103543. Available from: https://doi.org/10.1016/j.critrevonc.2021.103543
Saleh NE, Alhusseiny SM, El-Zayady WM, Aboelnaga EM, El-beshbishi WN, Saleh YM, et al. Trichomonas vaginalis serostatus and prostate cancer risk in Egypt: a case-control study. Parasitol Res [Internet]. 2021 Apr 1 [cited 2023 Sep 10];120(4):1379–88. Available from: https://pubmed.ncbi.nlm.nih.gov/33159459/

Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Angela Erquilia Upiachihua-del-Aguila

This work is licensed under a Creative Commons Attribution 4.0 International License.
The authors retain their rights:
a. The authors retain their trademark and patent rights, as well as any process or procedure described in the article.
b. The authors retain the right to share, copy, distribute, execute and publicly communicate the article published in the Revista Salud Amazónica y Bienestar (RSAYB) (for example, place it in an institutional repository or publish it in a book), with an acknowledgment of its initial publication in the RSAYB.
c. Authors retain the right to make a subsequent publication of their work, to use the article or any part of it (for example: a compilation of their works, notes for conferences, thesis, or for a book), provided that they indicate the source of publication (authors of the work, journal, volume, number and date).